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Regeneron International Science & Engineering Fair 2021

"The Regeneron International Science & Engineering Fair (ISEF) is an annual science fair held in the United States. Organised by the Society of Science, the fair hosts more than 1,800 students from over 70 countries and territories every May, and they compete for scholarships, awards and prizes. Due to the ongoing COVID-19 pandemic, the 2021 fair was replaced with an online version.

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Our project experimented with the use of Lactobacillus casei, a type of probiotics, to treat Alzheimer's disease in Drosophila melanogaster. We conducted locomotion, lifespan and eye phenotype tests, as well as brain imaging on fruit flies to reach conclusive results. Upon much research, L. casei, with its low cost and high possibility in treating the root cause of Alzheimer's, proved to be a promising and viable treatment method, which may be more accessible to patients suffering from this disease.

After rigorously reviewing our project materials and refining our presentation skills from what we have learnt from the Singapore Science & Engineering Fair, our project judging day (4 May 2021) finally arrived and it was time for us to engage the judges from all around the world. Through an online platform, we gave a short presentation and answered questions posed to us. Eventually, we were awarded the 2nd Award in the category of Animal Sciences!

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Our booth on the Regeneron Projectbooth website!
ISEF was definitely an eye-opening experience for all three of us. Through the project, we learnt the importance of teamwork and trust. It was only through our teammates' support and encouragement that we established newfound bravery and stepped out of our comfort zones. Moreover, research is never smooth-sailing, and despite having read many research journals, there are still many more things that we have yet to learn about. We realised that it was alright to admit that we did not know the answer to every question, even during the judging sessions! What is most important is our curiosity and courage to face the unknown.

We are very grateful to have been given the opportunity to work with experienced scientists and mentors who gave us invaluable feedback that helped us improve our research tremendously. ISEF was also an excellent chance for us to get to know peers from different parts of the world who share the same love for science!

We can undoubtedly say that this is one of the most fulfilling experiences that we have had. Passion is definitely an essential part of research and we are glad to have furthered our love for science through this fair. We earnestly urge everyone to seize opportunities and aim for the stars!"

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We could meet other ISEF finalists through an application called Eventfarm!
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That's us (from left) Low Iing, Celyn and Li Ann from RGS class of 2020!